- O-Lan Jones (3 films)
- O.E. Hasse (1 film)
- O.G. Dunn (2 films)
- O.L. Duke (1 film)
- O.S. Hawkins (1 film)
- O.Z. Whitehead (2 films)
- O'Neal Compton (1 film)
- O'Shea Jackson Jr. (7 films)
- Oakes Fegley (3 films)
- Oakley Bull (2 films)
- Oakley Lehman (1 film)
- Oakley Stevenson (1 film)
- oana Abur (1 film)
- Oana Maria Zaharia (1 film)
- Oana Pellea (3 films)
- Oanh Nguyen (1 film)
- Obba Babatunde (4 films)
- Obed Emvula (1 film)
- Obi Abili (1 film)
- Obinna Nwachukwu (1 film)
- Obioma Ugoala (1 film)
- Obrad Djurovic (1 film)
- Obssa Ahmed (1 film)
- Ocean James (1 film)
- Oceane Cairaty (1 film)
- Océane Mozas (1 film)
- Océane Rose Marie (1 film)
- Océane Slim (1 film)
- Ochuwa Oghie (1 film)
- Octave Bossuet (2 films)
- Octave Boussuet (1 film)
- Octave Novel (1 film)
- Octavia Chavez-Richmond (2 films)
- Octavia Selena Alexandru (1 film)
- Octavia Spencer (25 films)
- Octavian Cadia (1 film)
- Octavio Solis (1 film)
- Octavius J. Johnson (1 film)
- Odd Arno Midtsjø (1 film)
- Oddrun Valestrand (1 film)
- Oded Azulay (1 film)
- Oded Fehr (5 films)
- Oded Kotler (1 film)
- Oded Leopold (1 film)
- Oded Menaster (1 film)
- Odelya Halevi (1 film)
- Odera Adimorah (1 film)
- Odessa Munroe (1 film)
- Odessa Rae (2 films)
- Odessa Young (3 films)
